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Modification of the FoxP3 Transcription Factor Principally Affects Inducible T Regulatory Cells in a Model of Experimental Autoimmune Encephalomyelitis

T regulatory (Treg) cells expressing the transcription factor FoxP3 play a key role in protection against autoimmune disease. GFP-FoxP3 reporter mice have been used widely to study the induction, function and stability of both thymically- and peripherally-induced Treg cells. The N-terminal modificat...

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Detalles Bibliográficos
Autores principales:	Verhagen, Johan, Burton, Bronwen R., Britton, Graham J., Shepard, Ella R., Anderton, Stephen M., Wraith, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620162/ https://www.ncbi.nlm.nih.gov/pubmed/23593464 http://dx.doi.org/10.1371/journal.pone.0061334

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