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Modification of the FoxP3 Transcription Factor Principally Affects Inducible T Regulatory Cells in a Model of Experimental Autoimmune Encephalomyelitis
T regulatory (Treg) cells expressing the transcription factor FoxP3 play a key role in protection against autoimmune disease. GFP-FoxP3 reporter mice have been used widely to study the induction, function and stability of both thymically- and peripherally-induced Treg cells. The N-terminal modificat...
Autores principales: | Verhagen, Johan, Burton, Bronwen R., Britton, Graham J., Shepard, Ella R., Anderton, Stephen M., Wraith, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620162/ https://www.ncbi.nlm.nih.gov/pubmed/23593464 http://dx.doi.org/10.1371/journal.pone.0061334 |
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