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Knockdown of PPAR δ Gene Promotes the Growth of Colon Cancer and Reduces the Sensitivity to Bevacizumab in Nude Mice Model

The role of peroxisome proliferator – activated receptor- δ (PPAR δ) gene in colon carcinogenesis remains highly controversial. Here, we established nude mice xenograft model using a human colon cancer cell line KM12C either with PPAR δ silenced or normal. The xenografts in PPAR δ-silenced group gre...

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Detalles Bibliográficos
Autores principales:	Yang, Lie, Zhou, Jin, Ma, Qin, Wang, Cun, Chen, Keling, Meng, Wenjian, Yu, Yongyang, Zhou, Zongguang, Sun, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620168/ https://www.ncbi.nlm.nih.gov/pubmed/23593291 http://dx.doi.org/10.1371/journal.pone.0060715

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