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Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1
Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved dom...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620170/ https://www.ncbi.nlm.nih.gov/pubmed/23593419 http://dx.doi.org/10.1371/journal.pone.0061166 |