Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1

Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved dom...

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Detalles Bibliográficos
Autores principales: Lei, Lin, Ying, Sun, Baojun, Luo, Yi, Yang, Xiang, He, Wenli, Su, Zounan, Sun, Deyin, Guo, Qingyu, Zhu, Jingmei, Liu, Guohui, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620170/
https://www.ncbi.nlm.nih.gov/pubmed/23593419
http://dx.doi.org/10.1371/journal.pone.0061166

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