Anti-Thy-1 Antibody-mediated Complement-dependent Cytotoxicity is Regulated by the Distribution of Antigen, Antibody and Membrane Complement Regulatory Proteins in Rats

Some therapeutic antibodies as anticancer agents exert their effects through the host immune system, but the factors that predict their cytotoxicity, including complement-dependent cytotoxicity (CDC), are unclear. In the present study, we attempted to elucidate some of these factors in a preclinical...

Descripción completa

Detalles Bibliográficos
Autores principales: Kato, Chie, Kato, Atsuhiko, Adachi, Kenji, Fujii, Etsuko, Isobe, Kaori, Matsushita, Tomochika, Watanabe, Takeshi, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620213/
https://www.ncbi.nlm.nih.gov/pubmed/23723567
http://dx.doi.org/10.1293/tox.26.41

Ejemplares similares

Ejemplares similares