FoxO3a (Forkhead Box O3a) Deficiency Protects Idiopathic Pulmonary Fibrosis (IPF) Fibroblasts from Type I Polymerized Collagen Matrix-Induced Apoptosis via Caveolin-1 (cav-1) and Fas

Idiopathic Pulmonary Fibrosis is a lethal fibrotic disease characterized by the unrelenting proliferation and persistence of fibroblasts in a type I collagen-rich matrix that result in an expanding reticular network of fibrotic tissue. However, the underlying mechanism responsible for the persistenc...

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Detalles Bibliográficos
Autores principales: Nho, Richard Seonghun, Peterson, Mark, Hergert, Polla, Henke, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620276/
https://www.ncbi.nlm.nih.gov/pubmed/23580232
http://dx.doi.org/10.1371/journal.pone.0061017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620276/
https://www.ncbi.nlm.nih.gov/pubmed/23580232
http://dx.doi.org/10.1371/journal.pone.0061017

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