O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia

The development of resistance to chemotherapy is a major cause of relapse in acute lymphoblastic leukemia (ALL). Though several mechanisms associated with drug resistance have been studied in detail, the role of carbohydrate modification remains unexplored. Here, we investigated the contribution of...

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Detalles Bibliográficos
Autores principales: Parameswaran, Reshmi, Lim, Min, Arutyunyan, Anna, Abdel-Azim, Hisham, Hurtz, Christian, Lau, Kam, Müschen, Markus, Yu, Robert K., von Itzstein, Mark, Heisterkamp, Nora, Groffen, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620349/
https://www.ncbi.nlm.nih.gov/pubmed/23478187
http://dx.doi.org/10.1084/jem.20121482

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