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In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis

Expression of the pre–T cell receptor α (pTα) gene has been exploited in previous studies as a molecular marker to identify tiny cell populations in bone marrow (BM) and blood that were suggested to contain physiologically relevant thymus settling progenitors (TSPs). But to what extent these cells g...

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Detalles Bibliográficos
Autores principales: Luche, Hervé, Nageswara Rao, Tata, Kumar, Suresh, Tasdogan, Alpaslan, Beckel, Franziska, Blum, Carmen, Martins, Vera C., Rodewald, Hans-Reimer, Fehling, Hans Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620354/
https://www.ncbi.nlm.nih.gov/pubmed/23509324
http://dx.doi.org/10.1084/jem.20122609

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