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Carbon Monoxide Abrogates Ischemic Insult to Neuronal Cells via the Soluble Guanylate Cyclase-cGMP Pathway

PURPOSE: Carbon monoxide (CO) is an accepted cytoprotective molecule. The extent and mechanisms of protection in neuronal systems have not been well studied. We hypothesized that delivery of CO via a novel releasing molecule (CORM) would impart neuroprotection in vivo against ischemia-reperfusion in...

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Detalles Bibliográficos
Autores principales:	Schallner, Nils, Romão, Carlos C., Biermann, Julia, Lagrèze, Wolf A., Otterbein, Leo E., Buerkle, Hartmut, Loop, Torsten, Goebel, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620383/ https://www.ncbi.nlm.nih.gov/pubmed/23593279 http://dx.doi.org/10.1371/journal.pone.0060672

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