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Enhancing the Strength of an Optical Trap by Truncation
Optical traps (tweezers) are beginning to be used with increasing efficacy in diverse studies in the biological and biomedical sciences. We report here results of a systematic study aimed at enhancing the efficiency with which dielectric (transparent) materials can be optically trapped. Specifically...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620420/ https://www.ncbi.nlm.nih.gov/pubmed/23593458 http://dx.doi.org/10.1371/journal.pone.0061310 |
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author | Rodrigues, Vanessa R. M. Mondal, Argha Dharmadhikari, Jayashree A. Panigrahi, Swapnesh Mathur, Deepak Dharmadhikari, Aditya K. |
author_facet | Rodrigues, Vanessa R. M. Mondal, Argha Dharmadhikari, Jayashree A. Panigrahi, Swapnesh Mathur, Deepak Dharmadhikari, Aditya K. |
author_sort | Rodrigues, Vanessa R. M. |
collection | PubMed |
description | Optical traps (tweezers) are beginning to be used with increasing efficacy in diverse studies in the biological and biomedical sciences. We report here results of a systematic study aimed at enhancing the efficiency with which dielectric (transparent) materials can be optically trapped. Specifically, we investigate how truncation of the incident laser beam affects the strength of an optical trap in the presence of a circular aperture. Apertures of various sizes have been used by us to alter the beam radius, thereby changing the effective numerical aperture and intensity profile. We observe significant enhancement of the radial and axial trap stiffness when an aperture is used to truncate the beam compared to when no aperture was used, keeping incident laser power constant. Enhancement in trap stiffness persists even when the beam intensity profile is modulated. The possibility of applying truncation to multiple traps is explored; to this end a wire mesh is utilized to produce multiple trapping that also alters the effective numerical aperture. The use of a mesh leads to reduction in trap stiffness compared to the case when no wire mesh is used. Our findings lead to a simple-to-implement and inexpensive method of significantly enhancing optical trapping efficiency under a wide range of circumstances. |
format | Online Article Text |
id | pubmed-3620420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-36204202013-04-16 Enhancing the Strength of an Optical Trap by Truncation Rodrigues, Vanessa R. M. Mondal, Argha Dharmadhikari, Jayashree A. Panigrahi, Swapnesh Mathur, Deepak Dharmadhikari, Aditya K. PLoS One Research Article Optical traps (tweezers) are beginning to be used with increasing efficacy in diverse studies in the biological and biomedical sciences. We report here results of a systematic study aimed at enhancing the efficiency with which dielectric (transparent) materials can be optically trapped. Specifically, we investigate how truncation of the incident laser beam affects the strength of an optical trap in the presence of a circular aperture. Apertures of various sizes have been used by us to alter the beam radius, thereby changing the effective numerical aperture and intensity profile. We observe significant enhancement of the radial and axial trap stiffness when an aperture is used to truncate the beam compared to when no aperture was used, keeping incident laser power constant. Enhancement in trap stiffness persists even when the beam intensity profile is modulated. The possibility of applying truncation to multiple traps is explored; to this end a wire mesh is utilized to produce multiple trapping that also alters the effective numerical aperture. The use of a mesh leads to reduction in trap stiffness compared to the case when no wire mesh is used. Our findings lead to a simple-to-implement and inexpensive method of significantly enhancing optical trapping efficiency under a wide range of circumstances. Public Library of Science 2013-04-08 /pmc/articles/PMC3620420/ /pubmed/23593458 http://dx.doi.org/10.1371/journal.pone.0061310 Text en © 2013 Rodrigues et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Rodrigues, Vanessa R. M. Mondal, Argha Dharmadhikari, Jayashree A. Panigrahi, Swapnesh Mathur, Deepak Dharmadhikari, Aditya K. Enhancing the Strength of an Optical Trap by Truncation |
title | Enhancing the Strength of an Optical Trap by Truncation |
title_full | Enhancing the Strength of an Optical Trap by Truncation |
title_fullStr | Enhancing the Strength of an Optical Trap by Truncation |
title_full_unstemmed | Enhancing the Strength of an Optical Trap by Truncation |
title_short | Enhancing the Strength of an Optical Trap by Truncation |
title_sort | enhancing the strength of an optical trap by truncation |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620420/ https://www.ncbi.nlm.nih.gov/pubmed/23593458 http://dx.doi.org/10.1371/journal.pone.0061310 |
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