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Fyn Kinase Is Required for Optimal Humoral Responses

The generation of antigen-specific antibodies and the development of immunological memory require collaboration between B and T cells. T cell-secreted IL-4 is important for B cell survival, isotype switch to IgG1 and IgE, affinity maturation, and the development of germinal centers (GC). Fyn, a memb...

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Detalles Bibliográficos
Autores principales:	Chaimowitz, Natalia S., Falanga, Yves T., Ryan, John J., Conrad, Daniel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620480/ https://www.ncbi.nlm.nih.gov/pubmed/23593269 http://dx.doi.org/10.1371/journal.pone.0060640

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