Reversible alopecia in Vogt-Koyanagi-Harada disease and sympathetic ophthalmia

BACKGROUND: Vogt-Koyanagi-Harada (VKH) disease and sympathetic ophthalmia (SO) are both autoimmune disorders targeting melanin-bearing cells, even though their etiologies are different. Both shared many ocular and systemic manifestations, including integumentary findings. Most of the literature focu...

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Detalles Bibliográficos
Autores principales: Chuang, Chiu-Tung, Huang, Po-Sian, Chen, Shih-Chou, Sheu, Shwu-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620517/
https://www.ncbi.nlm.nih.gov/pubmed/23514340
http://dx.doi.org/10.1186/1869-5760-3-41
Descripción
Sumario:BACKGROUND: Vogt-Koyanagi-Harada (VKH) disease and sympathetic ophthalmia (SO) are both autoimmune disorders targeting melanin-bearing cells, even though their etiologies are different. Both shared many ocular and systemic manifestations, including integumentary findings. Most of the literature focused on the ocular manifestations and related treatment. Alopecia was seldom mentioned. FINDINGS: We report one case of VKH disease and one case of SO. Both developed severe alopecia and early sunset glow fundus, which are probably due to incomplete treatment. Fortunately, the alopecia improved soon after systemic steroid treatment. CONCLUSIONS: Early and complete treatments are important in the management of VKH or SO and prevent integumentary manifestation. Alopecia can be reversible after steroid treatment in time.

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