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Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells

BACKGROUND: For safe clinical application of engineered cartilage made from mesenchymal stem cells (MSCs), molecular mechanisms for chondrogenic differentiation must be known in detail. Changes in gene expression and extracellular matrix synthesis have been extensively studied, but the epigenomic mo...

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Detalles Bibliográficos
Autores principales:	Herlofsen, Sarah R, Bryne, Jan Christian, Høiby, Torill, Wang, Li, Issner, Robbyn, Zhang, Xiaolan, Coyne, Michael J, Boyle, Patrick, Gu, Hongcang, Meza-Zepeda, Leonardo A, Collas, Philippe, Mikkelsen, Tarjei S, Brinchmann, Jan E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620534/ https://www.ncbi.nlm.nih.gov/pubmed/23414147 http://dx.doi.org/10.1186/1471-2164-14-105

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