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An integrative network algorithm identifies age-associated differential methylation interactome hotspots targeting stem-cell differentiation pathways
Epigenetic changes have been associated with ageing and cancer. Identifying and interpreting epigenetic changes associated with such phenotypes may benefit from integration with protein interactome models. We here develop and validate a novel integrative epigenome-interactome approach to identify di...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620664/ https://www.ncbi.nlm.nih.gov/pubmed/23568264 http://dx.doi.org/10.1038/srep01630 |