Cargando…

Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes

Background: Endocrine-disrupting chemicals (EDCs) influence the activity of estrogen receptors (ERs) and alter the function of the endocrine system. However, the diversity of EDC effects and mechanisms of action are poorly understood. Objectives: We examined the agonistic activity of EDCs through ER...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yin, Luh, Colin J., Burns, Katherine A., Arao, Yukitomo, Jiang, Zhongliang, Teng, Christina T., Tice, Raymond R., Korach, Kenneth S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620735/ https://www.ncbi.nlm.nih.gov/pubmed/23384675 http://dx.doi.org/10.1289/ehp.1205951

Ejemplares similares

Differential Activation of a Mouse Estrogen Receptor β Isoform (mERβ2) with Endocrine-Disrupting Chemicals (EDCs)
por: Donoghue, Lauren J., et al.
Publicado: (2016)

Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor α and β in Vitro
por: Li, Yin, et al.
Publicado: (2012)

SUN-013 Estrogen Receptor Alpha Transactivation Function 1 Dependent Uterotropic Estrogenic Genes
por: Arao, Yukitomo, et al.
Publicado: (2019)

Transactivation Function-1-Mediated Partial Agonist Activity of Selective Estrogen Receptor Modulator Requires Homo-Dimerization of the Estrogen Receptor α Ligand Binding Domain
por: Arao, Yukitomo, et al.
Publicado: (2019)

GPER as a Receptor for Endocrine-Disrupting Chemicals (EDCs)
por: Périan, Séverine, et al.
Publicado: (2020)

Endocrine disrupting chemicals (EDCs) and female cancer: Informing the patients
por: Rachoń, Dominik
Publicado: (2016)

Combined Effects of Different Endocrine-Disrupting Chemicals (EDCs) on Prostate Gland
por: De Falco, Maria, et al.
Publicado: (2021)

N-terminal transactivation function, AF-1, of estrogen receptor alpha controls obesity through enhancement of energy expenditure
por: Arao, Yukitomo, et al.
Publicado: (2018)

Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?
por: Autrup, Herman, et al.
Publicado: (2020)

The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and in Vivo Uterine Responses via Estrogen Receptor α
por: Winuthayanon, Wipawee, et al.
Publicado: (2013)

Effects of Endocrine Disrupting Chemicals (EDCs) on Skeletal System Development: A Review
por: J, Chanemougavally, et al.
Publicado: (2023)

Exposure to endocrine disrupting chemicals (EDCs) and cardiometabolic indices during pregnancy: The HOME Study
por: Vuong, Ann M., et al.
Publicado: (2021)

Unlocking India’s Potential in Managing Endocrine-Disrupting Chemicals (EDCs): Importance, Challenges, and Opportunities
por: Sharma, Brij Mohan, et al.
Publicado: (2022)

Assessing dose–response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity
por: Zoeller, R Thomas, et al.
Publicado: (2015)

Endocrine-Disrupting Chemicals’ (EDCs) Effects on Tumour Microenvironment and Cancer Progression: Emerging Contribution of RACK1
por: Buoso, Erica, et al.
Publicado: (2020)

Do macrophages play a role in the adverse effects of endocrine disrupting chemicals (EDCs) on testicular functions?
por: Cui, Haoyi, et al.
Publicado: (2023)

Diarylheptanoid Phytoestrogens Isolated from the Medicinal Plant Curcuma comosa: Biologic Actions in Vitro and in Vivo Indicate Estrogen Receptor–Dependent Mechanisms
por: Winuthayanon, Wipawee, et al.
Publicado: (2009)

Hormone signaling and fatty liver in females: analysis of estrogen receptor α mutant mice
por: Hart-Unger, Sarah, et al.
Publicado: (2017)

EDCs and Estrogen Receptor Activity: A Pathway to Safer Chemical Design?
por: Barrett, Julia R.
Publicado: (2014)

Multi- and Transgenerational Outcomes of an Exposure to a Mixture of Endocrine-Disrupting Chemicals (EDCs) on Puberty and Maternal Behavior in the Female Rat
por: López-Rodríguez, David, et al.
Publicado: (2021)

Recent Trends in Multiclass Analysis of Emerging Endocrine Disrupting Contaminants (EDCs) in Drinking Water
por: Lazofsky, Abigail, et al.
Publicado: (2022)

Role of ERα in Mediating Female Uterine Transcriptional Responses to IGF1
por: Hewitt, Sylvia C., et al.
Publicado: (2017)

Herbicide Diuron as Endocrine Disrupting Chemicals (EDCs) through Histopathalogical Analysis in Gonads of Javanese Medaka (Oryzias javanicus, Bleeker 1854)
por: Kamarudin, Nur Amiera, et al.
Publicado: (2020)

Application of In Vitro Models for Studying the Mechanisms Underlying the Obesogenic Action of Endocrine-Disrupting Chemicals (EDCs) as Food Contaminants—A Review
por: Kowalczyk, Monika, et al.
Publicado: (2023)

Organization versus activation: the role of endocrine-disrupting contaminants (EDCs) during embryonic development in wildlife.
por: Guillette, L J, et al.
Publicado: (1995)

EDC IMPACT: Reduced sperm counts in rats exposed to human relevant mixtures of endocrine disrupters
por: Axelstad, M, et al.
Publicado: (2017)

OR06-03 Intergenerational Exposure To Endocrine-disrupting Chemicals (Edcs) Affects Dopamine-mediated Behaviors In A Sex-Specific Manner In Rats
por: Hilz, Emily N, et al.
Publicado: (2023)

Toxicological Mechanism of Endocrine Disrupting Chemicals:Is Estrogen Receptor Involved?
por: Jeung, Eui-Bae, et al.
Publicado: (2010)

Selected Fungicides as Potential EDC Estrogenic Micropollutants in the Environment
por: Jabłońska-Trypuć, Agata, et al.
Publicado: (2023)

Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting
por: Street, Maria Elisabeth, et al.
Publicado: (2018)

Estrogen Receptor beta (ERβ) Regulation of Lipid Homeostasis—Does Sex Matter?
por: Savva, Christina, et al.
Publicado: (2020)

Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways
por: Kerdivel, Gwenneg, et al.
Publicado: (2013)

Assessment of Five Pesticides as Endocrine-Disrupting Chemicals: Effects on Estrogen Receptors and Aromatase
por: Gea, Marta, et al.
Publicado: (2022)

SAT432 Interactions Of Endocrine-disrupting Chemical (EDC) Exposure And Fear Recall On Small Noncoding RNA (sncRNA) Contents Of Rat Caput Extracellular Vesicles
por: Gillette, Ross, et al.
Publicado: (2023)

New Tool for EDC Research: In Vivo Assay Screens for Estrogenic Effects
por: Arnold, Carrie
Publicado: (2015)

Commentary: “Estrogenic and Anti-Androgenic Endocrine Disrupting Chemicals and Their Impact on the Male Reproductive System”
por: Paumgartten, Francisco José Roma
Publicado: (2015)

Endocrine Disrupting Chemicals: Effects on Endocrine Glands
por: Lauretta, Rosa, et al.
Publicado: (2019)

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification
por: La Merrill, Michele A., et al.
Publicado: (2019)

Endocrine-Disrupting Chemicals and Infectious Diseases: From Endocrine Disruption to Immunosuppression
por: Adegoke, Elikanah Olusayo, et al.
Publicado: (2021)

Obesity and endocrine-disrupting chemicals
por: Amato, Angelica Amorim, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4o727js3kjo12rij2ujuc25qae