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Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy

Peripartum cardiomyopathy (PPCM) is a rare cause of pregnancy-related heart failure, which affects a woman during the last months of pregnancy or first months of parturition. Its etiopathogenesis is still unclear. Coexistence of PPCM with human immunodeficiency virus (HIV) has been scarcely analyzed...

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Autores principales: Mandal, Debasmita, Dattaray, Chaitalli, Dutta, Mousumi, Sarkar, Gouranga, Sinha, Pooja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621221/
https://www.ncbi.nlm.nih.gov/pubmed/23580922
http://dx.doi.org/10.4103/1995-705X.107117
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author Mandal, Debasmita
Dattaray, Chaitalli
Dutta, Mousumi
Sarkar, Gouranga
Sinha, Pooja
author_facet Mandal, Debasmita
Dattaray, Chaitalli
Dutta, Mousumi
Sarkar, Gouranga
Sinha, Pooja
author_sort Mandal, Debasmita
collection PubMed
description Peripartum cardiomyopathy (PPCM) is a rare cause of pregnancy-related heart failure, which affects a woman during the last months of pregnancy or first months of parturition. Its etiopathogenesis is still unclear. Coexistence of PPCM with human immunodeficiency virus (HIV) has been scarcely analyzed. A low CD4 count is proposed to be one of the predictors of dilated cardiomyopathy in HIV. Here, a pregnant woman with HIV presented with signs of congestive heart failure for the first time during her last trimester. Echocardiography revealed a dilated cardiomyopathy with ejection fraction of 34% which proved the diagnosis of PPCM. She underwent cesarean section for impending previous scar rupture. Her status deteriorated subsequently in spite of all efforts and she succumbed due to ventricular tachycardia. This case necessitates an awareness regarding coexistence of HIV with PPCM and dreaded clinical sequences. Patients suffering from HIV should be treated well and their CD4 count should be improved before conception to avoid such complications in pregnancy.
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spelling pubmed-36212212013-04-11 Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy Mandal, Debasmita Dattaray, Chaitalli Dutta, Mousumi Sarkar, Gouranga Sinha, Pooja Heart Views Case Report Peripartum cardiomyopathy (PPCM) is a rare cause of pregnancy-related heart failure, which affects a woman during the last months of pregnancy or first months of parturition. Its etiopathogenesis is still unclear. Coexistence of PPCM with human immunodeficiency virus (HIV) has been scarcely analyzed. A low CD4 count is proposed to be one of the predictors of dilated cardiomyopathy in HIV. Here, a pregnant woman with HIV presented with signs of congestive heart failure for the first time during her last trimester. Echocardiography revealed a dilated cardiomyopathy with ejection fraction of 34% which proved the diagnosis of PPCM. She underwent cesarean section for impending previous scar rupture. Her status deteriorated subsequently in spite of all efforts and she succumbed due to ventricular tachycardia. This case necessitates an awareness regarding coexistence of HIV with PPCM and dreaded clinical sequences. Patients suffering from HIV should be treated well and their CD4 count should be improved before conception to avoid such complications in pregnancy. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3621221/ /pubmed/23580922 http://dx.doi.org/10.4103/1995-705X.107117 Text en Copyright: © Heart Views http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mandal, Debasmita
Dattaray, Chaitalli
Dutta, Mousumi
Sarkar, Gouranga
Sinha, Pooja
Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy
title Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy
title_full Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy
title_fullStr Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy
title_full_unstemmed Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy
title_short Peripartum Cardiomyopathy Coexistent with Human Immunodeficiency Virus: A Substantial Obstetric Jeopardy
title_sort peripartum cardiomyopathy coexistent with human immunodeficiency virus: a substantial obstetric jeopardy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621221/
https://www.ncbi.nlm.nih.gov/pubmed/23580922
http://dx.doi.org/10.4103/1995-705X.107117
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