Encephalopathy secondary to isoniazid in patients on hemodialysis

We report isoniazid (INH)-induced encephalopathy in two male patients on hemodialysis. One of them had tuberculous adenitis, and the other had pulmonary tuberculosis. Both were given rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine 40 mg/day. Two patients developed disturbances in consc...

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Autores principales: Abbas, M. T., Khan, F. Y., Sulimon, S., Baidaa, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621241/
https://www.ncbi.nlm.nih.gov/pubmed/23580807
http://dx.doi.org/10.4103/0971-4065.107206
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author Abbas, M. T.
Khan, F. Y.
Sulimon, S.
Baidaa, A.
author_facet Abbas, M. T.
Khan, F. Y.
Sulimon, S.
Baidaa, A.
author_sort Abbas, M. T.
collection PubMed
description We report isoniazid (INH)-induced encephalopathy in two male patients on hemodialysis. One of them had tuberculous adenitis, and the other had pulmonary tuberculosis. Both were given rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine 40 mg/day. Two patients developed disturbances in consciousness. After excluding other causes, INH-induced encephalopathy was suspected so the drug was stopped and dose of pyridoxine increased. Both patients retained their consciousness within 1 week and were discharged.
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spelling pubmed-36212412013-04-11 Encephalopathy secondary to isoniazid in patients on hemodialysis Abbas, M. T. Khan, F. Y. Sulimon, S. Baidaa, A. Indian J Nephrol Case Report We report isoniazid (INH)-induced encephalopathy in two male patients on hemodialysis. One of them had tuberculous adenitis, and the other had pulmonary tuberculosis. Both were given rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine 40 mg/day. Two patients developed disturbances in consciousness. After excluding other causes, INH-induced encephalopathy was suspected so the drug was stopped and dose of pyridoxine increased. Both patients retained their consciousness within 1 week and were discharged. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3621241/ /pubmed/23580807 http://dx.doi.org/10.4103/0971-4065.107206 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Abbas, M. T.
Khan, F. Y.
Sulimon, S.
Baidaa, A.
Encephalopathy secondary to isoniazid in patients on hemodialysis
title Encephalopathy secondary to isoniazid in patients on hemodialysis
title_full Encephalopathy secondary to isoniazid in patients on hemodialysis
title_fullStr Encephalopathy secondary to isoniazid in patients on hemodialysis
title_full_unstemmed Encephalopathy secondary to isoniazid in patients on hemodialysis
title_short Encephalopathy secondary to isoniazid in patients on hemodialysis
title_sort encephalopathy secondary to isoniazid in patients on hemodialysis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621241/
https://www.ncbi.nlm.nih.gov/pubmed/23580807
http://dx.doi.org/10.4103/0971-4065.107206
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