Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series

ABSTRACT: A prospective multicentre clinical study was initiated to evaluate the safety and potential clinical benefit of non-invasive vagus nerve stimulation (nVNS) for the treatment of bronchoconstriction exacerbations in asthmatics. Due to slow enrolment and design changes of the device, the stud...

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Detalles Bibliográficos
Autores principales: Steyn, Elmin, Mohamed, Zunaid, Husselman, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621410/
https://www.ncbi.nlm.nih.gov/pubmed/23510361
http://dx.doi.org/10.1186/1865-1380-6-7
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author Steyn, Elmin
Mohamed, Zunaid
Husselman, Carla
author_facet Steyn, Elmin
Mohamed, Zunaid
Husselman, Carla
author_sort Steyn, Elmin
collection PubMed
description ABSTRACT: A prospective multicentre clinical study was initiated to evaluate the safety and potential clinical benefit of non-invasive vagus nerve stimulation (nVNS) for the treatment of bronchoconstriction exacerbations in asthmatics. Due to slow enrolment and design changes of the device, the study was prematurely terminated after enrolment of four eligible patients. Three of the four patients were considered treatment successes based on improvement in FEV(1), improvement in VAS dyspnoea scoring, and the absence of device-related adverse events. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01385306
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spelling pubmed-36214102013-04-10 Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series Steyn, Elmin Mohamed, Zunaid Husselman, Carla Int J Emerg Med Letter to the Editor ABSTRACT: A prospective multicentre clinical study was initiated to evaluate the safety and potential clinical benefit of non-invasive vagus nerve stimulation (nVNS) for the treatment of bronchoconstriction exacerbations in asthmatics. Due to slow enrolment and design changes of the device, the study was prematurely terminated after enrolment of four eligible patients. Three of the four patients were considered treatment successes based on improvement in FEV(1), improvement in VAS dyspnoea scoring, and the absence of device-related adverse events. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01385306 Springer 2013-03-19 /pmc/articles/PMC3621410/ /pubmed/23510361 http://dx.doi.org/10.1186/1865-1380-6-7 Text en Copyright ©2013 Steyn et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Steyn, Elmin
Mohamed, Zunaid
Husselman, Carla
Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
title Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
title_full Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
title_fullStr Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
title_full_unstemmed Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
title_short Non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
title_sort non-invasive vagus nerve stimulation for the treatment of acute asthma exacerbations—results from an initial case series
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621410/
https://www.ncbi.nlm.nih.gov/pubmed/23510361
http://dx.doi.org/10.1186/1865-1380-6-7
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