Cargando…
The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function
BACKGROUND: The acquisition of effective Vpu-mediated anti-tetherin activity to promote virion release following transmission of SIVcpzPtt from central chimpanzees (Pan troglodytes troglodytes) to humans distinguishes pandemic HIV-1 group M strains from non-pandemic group N, O and P viruses and may...
Autores principales: | Kluge, Silvia F, Sauter, Daniel, Vogl, Michael, Peeters, Martine, Li, Yingying, Bibollet-Ruche, Frederic, Hahn, Beatrice H, Kirchhoff, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621411/ https://www.ncbi.nlm.nih.gov/pubmed/23514615 http://dx.doi.org/10.1186/1742-4690-10-32 |
Ejemplares similares
-
Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu Protein
por: Sauter, Daniel, et al.
Publicado: (2012) -
Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance
por: Kmiec, Dorota, et al.
Publicado: (2016) -
The HIV-1 Vpu Viroporin Inhibitor BIT225 Does Not Affect Vpu-Mediated Tetherin Antagonism
por: Kuhl, Björn D., et al.
Publicado: (2011) -
Vpu Downmodulates Two Distinct Targets, Tetherin and Gibbon Ape Leukemia Virus Envelope, through Shared Features in the Vpu Cytoplasmic Tail
por: Lucas, Tiffany M., et al.
Publicado: (2012) -
Anti-tetherin activities in Vpu-expressing primate lentiviruses
por: Yang, Su Jung, et al.
Publicado: (2010)