SynGAP isoforms exert opposing effects on synaptic strength

Alternative promoter usage and alternative splicing enable diversification of the transcriptome. Here we demonstrate that the function of Synaptic GTPase-Activating Protein (SynGAP), a key synaptic protein, is determined by the combination of its amino-terminal sequence with its carboxy-terminal seq...

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Detalles Bibliográficos
Autores principales: McMahon, A.C., Barnett, M.W., O'Leary, T.S., Stoney, P.N., Collins, M.O., Papadia, S., Choudhary, J.S., Komiyama, N.H., Grant, S.G.N., Hardingham, G.E., Wyllie, D.J.A., Kind, P.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621422/
https://www.ncbi.nlm.nih.gov/pubmed/22692543
http://dx.doi.org/10.1038/ncomms1900

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