Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation

BACKGROUND: Genetic susceptibility to colonic inflammation is poorly defined at the gene level. Although Genome Wide Association studies (GWAS) have identified loci in the human genome which confer susceptibility to Inflammatory Bowel Disease (Crohn’s and Ulcerative Colitis), it is not clear if prec...

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Detalles Bibliográficos
Autores principales: Levison, Scott E, Fisher, Paul, Hankinson, Jenny, Zeef, Leo, Eyre, Steve, Ollier, William E, McLaughlin, John T, Brass, Andy, Grencis, Richard K, Pennock, Joanne L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621453/
https://www.ncbi.nlm.nih.gov/pubmed/23442222
http://dx.doi.org/10.1186/1471-2164-14-127

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