Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei

[Image: see text] The protozoan parasite Trypanosoma brucei is the causative agent of African sleeping sickness, and there is an urgent unmet need for improved treatments. Parasite protein kinases are attractive drug targets, provided that the host and parasite kinomes are sufficiently divergent to...

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Detalles Bibliográficos
Autores principales: Urbaniak, Michael D., Mathieson, Toby, Bantscheff, Marcus, Eberhard, Dirk, Grimaldi, Raffaella, Miranda-Saavedra, Diego, Wyatt, Paul, Ferguson, Michael A. J., Frearson, Julie, Drewes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621575/
https://www.ncbi.nlm.nih.gov/pubmed/22908928
http://dx.doi.org/10.1021/cb300326z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621575/
https://www.ncbi.nlm.nih.gov/pubmed/22908928
http://dx.doi.org/10.1021/cb300326z

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