Cargando…

The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer

BACKGROUND: Acquired resistance to Tamoxifen remains a critical problem in breast cancer patient treatment, yet the underlying causes of resistance have not been fully elucidated. Abberations in the Wnt signalling pathway have been linked to many human cancers, including breast cancer, and appear to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Loh, Yan Ni, Hedditch, Ellen L, Baker, Laura A, Jary, Eve, Ward, Robyn L, Ford, Caroline E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621642/ https://www.ncbi.nlm.nih.gov/pubmed/23547709 http://dx.doi.org/10.1186/1471-2407-13-174

Ejemplares similares

The Wnt Gatekeeper SFRP4 Modulates EMT, Cell Migration and Downstream Wnt Signalling in Serous Ovarian Cancer Cells
por: Ford, Caroline E., et al.
Publicado: (2013)

AFF3 upregulation mediates tamoxifen resistance in breast cancers
por: Shi, Yawei, et al.
Publicado: (2018)

Acquired Bilateral Nevoid Telangiectasia Induced by Tamoxifen
por: Navarro-Navarro, Irene, et al.
Publicado: (2023)

Tamoxifen metabolism: pharmacokinetic and in vitro study.
por: Etienne, M. C., et al.
Publicado: (1989)

Reversal of acquired resistance to adriamycin in CHO cells by tamoxifen and 4-hydroxy tamoxifen: role of drug interaction with alpha 1 acid glycoprotein.
por: Chatterjee, M., et al.
Publicado: (1990)

Development, Characterization, and In Vitro Evaluation of Tamoxifen Microemulsions
por: Monteagudo, E., et al.
Publicado: (2012)

Leptin promotes the growth of breast cancer by upregulating the Wnt/β-catenin pathway
por: Liang, Xi, et al.
Publicado: (2018)

A Platelet Acquired Storage Pool Disorder Associated with Tamoxifen Therapy
por: Nayak, Lalitha, et al.
Publicado: (2012)

Wnt Signaling Upregulates Teneurin-3 Expression via Canonical and Non-canonical Wnt Pathway Crosstalk
por: Bastías-Candia, Sussy, et al.
Publicado: (2019)

Continuous Exposure of Breast Cancer Cells to Tamoxifen Upregulates GPER-1 and Increases Cell Proliferation
por: Molina, Luis, et al.
Publicado: (2020)

Cytotoxicity of tamoxifen for acute lymphoblastic leukaemia in vitro.
por: Blatt, J., et al.
Publicado: (1984)

Tamoxifen activity against Plasmodium in vitro and in mice
por: Weinstock, Ada, et al.
Publicado: (2019)

MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit
por: Løkkegaard, Sanne, et al.
Publicado: (2021)

Overexpression of CD44 in acquired tamoxifen-resistant breast cancer cells augments their migratory response to heregulin beta 1
por: Hiscox, S, et al.
Publicado: (2008)

Fibronectin expression is upregulated by PI-3K/Akt activation in tamoxifen-resistant breast cancer cells
por: You, Daeun, et al.
Publicado: (2017)

Knockdown of Long Non-Coding RNA UCA1 Increases the Tamoxifen Sensitivity of Breast Cancer Cells through Inhibition of Wnt/β-Catenin Pathway
por: Liu, Hongying, et al.
Publicado: (2016)

Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway
por: Fu, Yijie, et al.
Publicado: (2020)

The Effect and Mechanism of Tamoxifen-Induced Hepatocyte Steatosis in Vitro
por: Zhao, Fei, et al.
Publicado: (2014)

Tamoxifen Induces Apoptosis of Leishmania major Promastigotes in Vitro
por: Doroodgar, Masoud, et al.
Publicado: (2016)

Expression of the CD59 Glycoprotein Precursor is Upregulated in an Estrogen Receptor-alpha (ER-α)-Negative and a Tamoxifen-Resistant Breast Cancer Cell Line In Vitro
por: Xiong, Huiru, et al.
Publicado: (2018)

Wnt pathway inhibitors are upregulated in XLH dental pulp cells in response to odontogenic differentiation
por: Guirado, Elizabeth, et al.
Publicado: (2023)

Resuming Sensitivity of Tamoxifen-Resistant Breast Cancer Cells to Tamoxifen by Tetrandrine
por: Wang, Yuntao, et al.
Publicado: (2021)

Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer
por: Kim, Hyeon Woo, et al.
Publicado: (2022)

Histiocytic lymphoma of breast responds to tamoxifen.
por: Millis, R. R., et al.
Publicado: (1988)

Surgery, with or without tamoxifen, vs tamoxifen alone for older women with operable breast cancer: Cochrane review
por: Hind, D, et al.
Publicado: (2007)

Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance
por: Zhu, Jing, et al.
Publicado: (2022)

GSK-3β suppresses HCC cell dissociation in vitro by upregulating epithelial junction proteins and inhibiting Wnt/β-catenin signaling pathway
por: Zhang, Jing-Hua, et al.
Publicado: (2017)

Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway
por: Liu, Bing, et al.
Publicado: (2021)

Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1
por: Zhu, Yinghua, et al.
Publicado: (2018)

Plumbagin sensitizes breast cancer cells to tamoxifen-induced cell death through GRP78 inhibition and Bik upregulation
por: Kawiak, Anna, et al.
Publicado: (2017)

Bryostatin 1-tamoxifen combinations show synergistic effects on the inhibition of growth of P388 cells in vitro.
por: McGown, A. T., et al.
Publicado: (1998)

Tamoxifen Resistance in Breast Cancer
por: Chang, Minsun
Publicado: (2012)

Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells
por: Moon, Seo Yun, et al.
Publicado: (2021)

IARC on tamoxifen.
Publicado: (1996)

Tamoxifen evolution
por: Howell, A., et al.
Publicado: (2023)

Dramatic dysbalancing of the Wnt pathway in breast cancers
por: Koval, Alexey, et al.
Publicado: (2018)

Upregulation of PI3K/AKT/PTEN pathway is correlated with glucose and glutamine metabolic dysfunction during tamoxifen resistance development in MCF-7 cells
por: Hamadneh, Lama, et al.
Publicado: (2020)

Investigating the molecular mechanisms of Tamoxifen on the EMT pathway among patients with breast cancer
por: Mirzaei, Mohammadhossein, et al.
Publicado: (2022)

Tranilast enhances the anti-tumor effects of tamoxifen on human breast cancer cells in vitro
por: Darakhshan, Sara, et al.
Publicado: (2013)

The Effect of Canertinib on Sensitivity of Cytotoxic Drugs in Tamoxifen-Resistant Breast Cancer Cells In Vitro
por: Gomaa, Hesham A. M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6l7jodh77suupnk79c77g5dapc