Cargando…

Adenoviral Gene Transfer of PLD1-D4 Enhances Insulin Sensitivity in Mice by Disrupting Phospholipase D1 Interaction with PED/PEA-15

Over-expression of phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes (PED/PEA-15) causes insulin resistance by interacting with the D4 domain of phospholipase D1 (PLD1). Indeed, the disruption of this association restores insulin sensitivity in cultured cells over-expressing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cassese, Angela, Raciti, Gregory A., Fiory, Francesca, Nigro, Cecilia, Ulianich, Luca, Castanò, Ilenia, D’Esposito, Vittoria, Terracciano, Daniela, Pastore, Lucio, Formisano, Pietro, Beguinot, Francesco, Miele, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621763/ https://www.ncbi.nlm.nih.gov/pubmed/23585839 http://dx.doi.org/10.1371/journal.pone.0060555

Ejemplares similares

PED/PEA-15 Inhibits Hydrogen Peroxide-Induced Apoptosis in Ins-1E Pancreatic Beta-Cells via PLD-1
por: Fiory, Francesca, et al.
Publicado: (2014)

Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice
por: Perruolo, Giuseppe, et al.
Publicado: (2016)

Expression of Concern: Adenoviral Gene Transfer of PLD1-D4 Enhances Insulin Sensitivity in Mice by Disrupting Phospholipase D1 Interaction with PED/PEA-15
Publicado: (2022)

PED/PEA-15 Controls Fibroblast Motility and Wound Closure by ERK1/2-Dependent Mechanisms
por: Buonomo, Roberta, et al.
Publicado: (2012)

Clozapine Impairs Insulin Action by Up-Regulating Akt Phosphorylation and Ped/Pea-15 Protein Abundance
por: Panariello, Fabio, et al.
Publicado: (2012)

PED/PEA-15 interacts with the 67 kD laminin receptor and regulates cell adhesion, migration, proliferation and apoptosis
por: Formisano, Pietro, et al.
Publicado: (2012)

Diabetes and Cognitive Impairment: A Role for Glucotoxicity and Dopaminergic Dysfunction
por: Pignalosa, Francesca Chiara, et al.
Publicado: (2021)

Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity
por: Raciti, Gregory A., et al.
Publicado: (2017)

PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation
por: Iovino, S, et al.
Publicado: (2012)

Serum 25-Hydroxyvitamin D Levels, phosphoprotein enriched in diabetes gene product (PED/PEA-15) and leptin-to-adiponectin ratio in women with PCOS
por: Savastano, Silvia, et al.
Publicado: (2011)

Platelet‐Rich Plasma Increases Growth and Motility of Adipose Tissue‐Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function
por: D'Esposito, Vittoria, et al.
Publicado: (2015)

Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib
por: Quintavalle, Cristina, et al.
Publicado: (2017)

Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells
por: Raciti, Gregory Alexander, et al.
Publicado: (2018)

Dopamine-Induced Plasticity, Phospholipase D (PLD) Activity and Cocaine-Cue Behavior Depend on PLD-Linked Metabotropic Glutamate Receptors in Amygdala
por: Krishnan, Balaji, et al.
Publicado: (2011)

Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease
por: Cimmino, Ilaria, et al.
Publicado: (2020)

Interfering PLD1-PED/PEA15 interaction using self-inhibitory peptides: An in silico study to discover novel therapeutic candidates against type 2 diabetes
por: Baig, Mohammad Hassan, et al.
Publicado: (2019)

Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage
por: Nigro, Cecilia, et al.
Publicado: (2017)

The Destiny of Glucose from a MicroRNA Perspective
por: Mirra, Paola, et al.
Publicado: (2018)

Mammary Adipose Tissue Control of Breast Cancer Progression: Impact of Obesity and Diabetes
por: D’Esposito, Vittoria, et al.
Publicado: (2020)

Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50:1244–1252. DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323
por: Condorelli, Gerolama, et al.
Publicado: (2018)

Amygdala-Hippocampal Phospholipase D (PLD) Signaling As Novel Mechanism of Cocaine-Environment Maladaptive Conditioned Responses
por: Krishnan, Balaji
Publicado: (2016)

Metformin Dysregulates the Unfolded Protein Response and the WNT/β-Catenin Pathway in Endometrial Cancer Cells through an AMPK-Independent Mechanism
por: Conza, Domenico, et al.
Publicado: (2021)

Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer
por: Conza, Domenico, et al.
Publicado: (2023)

Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity
por: Longo, Michele, et al.
Publicado: (2017)

Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging
por: Nigro, Cecilia, et al.
Publicado: (2019)

PHOSPHOLIPASE D (PLD) DRIVES CELL INVASION, TUMOR GROWTH AND METASTASIS IN A HUMAN BREAST CANCER XENOGRAPH MODEL
por: Henkels, Karen M., et al.
Publicado: (2013)

PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer’s disease
por: Nackenoff, Alex G., et al.
Publicado: (2021)

The Relevance of Insulin Action in the Dopaminergic System
por: Fiory, Francesca, et al.
Publicado: (2019)

Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro
por: D’Esposito, V., et al.
Publicado: (2012)

Proteomic Analysis of Arabidopsis pldα1 Mutants Revealed an Important Role of Phospholipase D Alpha 1 in Chloroplast Biogenesis
por: Takáč, Tomáš, et al.
Publicado: (2019)

ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first‐degree relatives of type 2 diabetics
por: Spinelli, Rosa, et al.
Publicado: (2022)

Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner
por: Wettstadt, Sarah, et al.
Publicado: (2019)

PEA-15 potentiates H-Ras mediated epithelial cell transformation through Phospholipase D
por: Sulzmaier, Florian J., et al.
Publicado: (2011)

miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal
por: Nigro, Cecilia, et al.
Publicado: (2018)

Genome-Wide Analysis of the Phospholipase D Family in Five Cotton Species, and Potential Role of GhPLD2 in Fiber Development and Anther Dehiscence
por: Ma, Changkai, et al.
Publicado: (2021)

Genome-wide in silico identification of phospholipase D (PLD) gene family from Corchorus capsularis and Corchorus olitorius: reveals their responses to plant stress
por: Sadat, Md. Abu, et al.
Publicado: (2022)

Expression of Concern. The IR(1152) Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49:1194–1202. DOI: 10.2337/diabetes.49.7.1194. PMID: 10909978
por: Caruso, Matilde, et al.
Publicado: (2018)

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications
por: Longo, Michele, et al.
Publicado: (2019)

The Dual-Role of Methylglyoxal in Tumor Progression – Novel Therapeutic Approaches
por: Leone, Alessia, et al.
Publicado: (2021)

The Escherichia coli Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling
por: May, Kerrie L., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_m673khbgl3moco53src0ovs1p5