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A functional genomics screen for microRNA regulators of NF-kappaB signaling
BACKGROUND: The nuclear factor-KappaB (NF-κB) pathway is conserved from fruit flies to humans and is a key mediator of inflammatory signaling. Aberrant regulation of NF-κB is associated with several disorders including autoimmune disease, chronic inflammation, and cancer, making the NF-κB pathway an...
Autores principales: | Olarerin-George, Anthony O, Anton, Lauren, Hwang, Yih-Chii, Elovitz, Michal A, Hogenesch, John B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621838/ https://www.ncbi.nlm.nih.gov/pubmed/23448136 http://dx.doi.org/10.1186/1741-7007-11-19 |
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