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A functional genomics screen for microRNA regulators of NF-kappaB signaling

BACKGROUND: The nuclear factor-KappaB (NF-κB) pathway is conserved from fruit flies to humans and is a key mediator of inflammatory signaling. Aberrant regulation of NF-κB is associated with several disorders including autoimmune disease, chronic inflammation, and cancer, making the NF-κB pathway an...

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Detalles Bibliográficos
Autores principales: Olarerin-George, Anthony O, Anton, Lauren, Hwang, Yih-Chii, Elovitz, Michal A, Hogenesch, John B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621838/
https://www.ncbi.nlm.nih.gov/pubmed/23448136
http://dx.doi.org/10.1186/1741-7007-11-19

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