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Galectin-9 Ameliorates Clinical Severity of MRL/lpr Lupus-Prone Mice by Inducing Plasma Cell Apoptosis Independently of Tim-3
Galectin-9 ameliorates various murine autoimmune disease models by regulating T cells and macrophages, although it is not known what role it may have in B cells. The present experiment shows that galectin-9 ameliorates a variety of clinical symptoms, such as proteinuria, arthritis, and hematocrit in...
Autores principales: | Moritoki, Masahiro, Kadowaki, Takeshi, Niki, Toshiro, Nakano, Daisuke, Soma, Genichiro, Mori, Hirohito, Kobara, Hideki, Masaki, Tsutomu, Kohno, Masakazu, Hirashima, Mitsuomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621869/ https://www.ncbi.nlm.nih.gov/pubmed/23585851 http://dx.doi.org/10.1371/journal.pone.0060807 |
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