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PMS1077 Sensitizes TNF-α Induced Apoptosis in Human Prostate Cancer Cells by Blocking NF-κB Signaling Pathway

Our previous studies have demonstrated that PMS1077, a platelet-activating factor (PAF) antagonist, could induce apoptosis of Raji cells. However, the mechanism of action has not yet been determined. The nuclear transcription factor-kappa B (NF-κB) signaling pathway plays a critical role in tumor ce...

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Detalles Bibliográficos
Autores principales: Shi, Jie, Chen, Jing, Serradji, Nawal, Xu, Ximing, Zhou, Heng, Ma, Yinxing, Sun, Zhihong, Jiang, Peng, Du, Yuping, Yang, Jinbo, Dong, Changzhi, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621893/
https://www.ncbi.nlm.nih.gov/pubmed/23593410
http://dx.doi.org/10.1371/journal.pone.0061132