Cargando…

Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells

TRPC5 is a member of the canonical transient receptor potential (TRPC) family of proteins that forms cationic channels either through homomultimeric assembly or heteromultimeric coordination with other TRPC proteins. It is expressed in a variety of cells including central neurones and endothelial ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, Ching-On, Sukumar, Piruthivi, Beech, David J., Yao, Xiaoqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Ion Channels, Receptors and Transporters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622007/ https://www.ncbi.nlm.nih.gov/pubmed/20390293 http://dx.doi.org/10.1007/s00424-010-0823-3

Ejemplares similares

Interspecies differences in PTH-mediated PKA phosphorylation of the epithelial calcium channel TRPV5
por: van Goor, Mark K, et al.
Publicado: (2017)

Endothelial-dependent dilation following chronic hypoxia involves TRPV4-mediated activation of endothelial BK channels
por: Naik, Jay S., et al.
Publicado: (2018)

Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity
por: Povstyan, Oleksandr V., et al.
Publicado: (2016)

Neuronal nitric oxide synthase regulation of calcium cycling in ventricular cardiomyocytes is independent of Ca(v)1.2 channel modulation under basal conditions
por: Ebner, Janine, et al.
Publicado: (2019)

A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P(2)
por: Telezhkin, Vsevolod, et al.
Publicado: (2013)

Na(+)/Ca(2+) exchangers and Orai channels jointly refill endoplasmic reticulum (ER) Ca(2+) via ER nanojunctions in vascular endothelial cells
por: Di Giuro, Cristiana M. L., et al.
Publicado: (2017)

CO(2)-dependent opening of an inwardly rectifying K(+) channel
por: Huckstepp, Robert T. R., et al.
Publicado: (2011)

Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S
por: Haerteis, Silke, et al.
Publicado: (2012)

Characterization of distinct single-channel properties of Ca(2+) inward currents in mitochondria
por: Bondarenko, Alexander I., et al.
Publicado: (2013)

Impact of intracellular hemin on N-type inactivation of voltage-gated K(+) channels
por: Coburger, Ina, et al.
Publicado: (2020)

Determinants of the voltage dependence of G protein modulation within calcium channel β subunits
por: Dresviannikov, Andriy V., et al.
Publicado: (2008)

TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model
por: Venturi, Elisa, et al.
Publicado: (2013)

Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain
por: de la Peña, Pilar, et al.
Publicado: (2018)

The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores
por: Zong, Xiangang, et al.
Publicado: (2009)

UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria
por: Bondarenko, Alexander I., et al.
Publicado: (2015)

The TRPV3 channel of the bovine rumen: localization and functional characterization of a protein relevant for ruminal ammonia transport
por: Liebe, Franziska, et al.
Publicado: (2020)

Functional expression of mitochondrial K(Ca)3.1 channels in non-small cell lung cancer cells
por: Bulk, Etmar, et al.
Publicado: (2022)

Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels
por: Lin, JinHeng, et al.
Publicado: (2022)

Mitochondrial Ca(2+) uniporter (MCU)-dependent and MCU-independent Ca(2+) channels coexist in the inner mitochondrial membrane
por: Bondarenko, Alexander I., et al.
Publicado: (2013)

Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study
por: Veeraraghavan, Rengasayee, et al.
Publicado: (2015)

Effects of syntaxins 2, 3, and 4 on rat and human epithelial sodium channel (ENaC) in Xenopus laevis oocytes
por: Rauh, Robert, et al.
Publicado: (2020)

The bile acid-sensitive ion channel (BASIC) mediates bile acid-dependent currents in bile duct epithelial cells
por: Wiegreffe, Shari, et al.
Publicado: (2021)

Effects of butyrate(−) on ruminal Ca(2+) transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels
por: Liebe, Franziska, et al.
Publicado: (2022)

Loss of the large conductance calcium-activated potassium channel causes an increase in mitochondrial reactive oxygen species in glioblastoma cells
por: Kulawiak, Bogusz, et al.
Publicado: (2023)

α-ENaC is a functional element of the hypertonicity-induced cation channel in HepG2 cells and it mediates proliferation
por: Bondarava, Maryna, et al.
Publicado: (2009)

RBP2 stabilizes slow Cav1.3 Ca(2+) channel inactivation properties of cochlear inner hair cells
por: Ortner, Nadine J., et al.
Publicado: (2019)

Synergistic effects of agonists and two-pore-domain potassium channels on secretory responses of human pancreatic duct cells Capan-1
por: Sørensen, Christiane E., et al.
Publicado: (2022)

Activation of the Ca(2+)-sensing receptors increases currents through inward rectifier K(+) channels via activation of phosphatidylinositol 4-kinase
por: Liu, Chung-Hung, et al.
Publicado: (2016)

Gating mechanism of Kv11.1 (hERG) K(+) channels without covalent connection between voltage sensor and pore domains
por: de la Peña, Pilar, et al.
Publicado: (2017)

Pendrin abundance, subcellular distribution, and function are unaffected by either αENaC gene ablation or by increasing ENaC channel activity
por: Loffing, Johannes, et al.
Publicado: (2023)

Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice
por: Artunc, Ferruh, et al.
Publicado: (2021)

Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation
por: Kirchhoff, Jeppe Egedal, et al.
Publicado: (2016)

Channelopathies in Ca(v)1.1, Ca(v)1.3, and Ca(v)1.4 voltage-gated L-type Ca(2+) channels
por: Striessnig, Jörg, et al.
Publicado: (2010)

KCNE1 does not shift TMEM16A from a Ca(2+) dependent to a voltage dependent Cl(-) channel and is not expressed in renal proximal tubule
por: Talbi, Khaoula, et al.
Publicado: (2023)

Structural basis of PI(4,5)P(2)-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A)
por: Seebohm, Guiscard, et al.
Publicado: (2014)

Enhanced Ca(2+) influx through cardiac L-type Ca(2+) channels maintains the systolic Ca(2+) transient in early cardiac atrophy induced by mechanical unloading
por: Schwoerer, A. P., et al.
Publicado: (2013)

Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α(2)δ-1-induced downregulation of Ca(v)1.2 channels
por: Rougier, Jean-Sebastien, et al.
Publicado: (2014)

Guanosine modulates K(+) membrane currents in SH-SY5Y cells: involvement of adenosine receptors
por: Gambino, Giuditta, et al.
Publicado: (2022)

Ion transporters in brain endothelial cells that contribute to formation of brain interstitial fluid
por: Mokgokong, Ruth, et al.
Publicado: (2013)

Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation
por: Tambeaux, Allison, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eikgae4lahehj1pv7lm7v7scn2