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NF-κB Plays a Key Role in Inducing CD274 Expression in Human Monocytes after Lipopolysaccharide Treatment

CD274, one of two co-stimulatory ligands for programmed death 1 and widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells and regulates inflammatory responses. However, changes in CD274 gene expression and the underlying molecular mechanism are poorly understood during...

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Detalles Bibliográficos
Autores principales: Huang, Gang, Wen, Qianjun, Zhao, Yongliang, Gao, Qiangguo, Bai, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622012/
https://www.ncbi.nlm.nih.gov/pubmed/23585913
http://dx.doi.org/10.1371/journal.pone.0061602