Recurrent Exposure to Subclinical Lipopolysaccharide Increases Mortality and Induces Cardiac Fibrosis in Mice

BACKGROUND: Circulating subclinical lipopolysaccharide (LPS) occurs in health and disease. Ingesting high fatty meals increases LPS that cause metabolic endotoxemia. Subclinical LPS in periodontal disease may impair endothelial function. The heart may be targeted as cardiac cells express TLR4, the L...

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Detalles Bibliográficos
Autores principales: Lew, Wilbur Y. W., Bayna, Evelyn, Molle, Erminia Dalle, Dalton, Nancy D., Lai, N. Chin, Bhargava, Valmik, Mendiola, Vincent, Clopton, Paul, Tang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622013/
https://www.ncbi.nlm.nih.gov/pubmed/23585870
http://dx.doi.org/10.1371/journal.pone.0061057

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