Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function

The actin crosslinking protein filamin A (FLNa) mediates mechanotransduction, a conversion of mechanical forces into cellular biochemical signals to regulate cell growth and survival. To provide more quantitative insight into this process, we report results using magnetic tweezers that relate mechan...

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Detalles Bibliográficos
Autores principales: Chen, Hu, Chandrasekar, Saranya, Sheetz, Michael P., Stossel, Thomas P., Nakamura, Fumihiko, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622079/
https://www.ncbi.nlm.nih.gov/pubmed/23571456
http://dx.doi.org/10.1038/srep01642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622079/
https://www.ncbi.nlm.nih.gov/pubmed/23571456
http://dx.doi.org/10.1038/srep01642

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