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Designer antiandrogens join the race against drug resistance
By using in silico models of the complexes formed by analogues of a cancer drug and its receptor, it may be possible to strategically redesign existing drugs and win the race against mutations that lead to drug resistance in prostate cancer.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622176/ https://www.ncbi.nlm.nih.gov/pubmed/23580166 http://dx.doi.org/10.7554/eLife.00692 |
| _version_ | 1782265809549131776 |
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| author | Josan, Jatinder S Katzenellenbogen, John A |
| author_facet | Josan, Jatinder S Katzenellenbogen, John A |
| author_sort | Josan, Jatinder S |
| collection | PubMed |
| description | By using in silico models of the complexes formed by analogues of a cancer drug and its receptor, it may be possible to strategically redesign existing drugs and win the race against mutations that lead to drug resistance in prostate cancer. |
| format | Online Article Text |
| id | pubmed-3622176 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | eLife Sciences Publications, Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-36221762013-04-11 Designer antiandrogens join the race against drug resistance Josan, Jatinder S Katzenellenbogen, John A eLife Human Biology and Medicine By using in silico models of the complexes formed by analogues of a cancer drug and its receptor, it may be possible to strategically redesign existing drugs and win the race against mutations that lead to drug resistance in prostate cancer. eLife Sciences Publications, Ltd 2013-04-09 /pmc/articles/PMC3622176/ /pubmed/23580166 http://dx.doi.org/10.7554/eLife.00692 Text en Copyright © 2013, Josan and Katzenellenbogen http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
| spellingShingle | Human Biology and Medicine Josan, Jatinder S Katzenellenbogen, John A Designer antiandrogens join the race against drug resistance |
| title | Designer antiandrogens join the race against drug resistance |
| title_full | Designer antiandrogens join the race against drug resistance |
| title_fullStr | Designer antiandrogens join the race against drug resistance |
| title_full_unstemmed | Designer antiandrogens join the race against drug resistance |
| title_short | Designer antiandrogens join the race against drug resistance |
| title_sort | designer antiandrogens join the race against drug resistance |
| topic | Human Biology and Medicine |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622176/ https://www.ncbi.nlm.nih.gov/pubmed/23580166 http://dx.doi.org/10.7554/eLife.00692 |
| work_keys_str_mv | AT josanjatinders designerantiandrogensjointheraceagainstdrugresistance AT katzenellenbogenjohna designerantiandrogensjointheraceagainstdrugresistance |