Cargando…

Shedding new light on circadian clocks

Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains.

Detalles Bibliográficos
Autores principales: Demarque, Maud, Schibler, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622228/
https://www.ncbi.nlm.nih.gov/pubmed/23580350
http://dx.doi.org/10.7554/eLife.00659
_version_ 1782265810707808256
author Demarque, Maud
Schibler, Ueli
author_facet Demarque, Maud
Schibler, Ueli
author_sort Demarque, Maud
collection PubMed
description Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains.
format Online
Article
Text
id pubmed-3622228
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-36222282013-04-11 Shedding new light on circadian clocks Demarque, Maud Schibler, Ueli eLife Genomics and Evolutionary Biology Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains. eLife Sciences Publications, Ltd 2013-04-09 /pmc/articles/PMC3622228/ /pubmed/23580350 http://dx.doi.org/10.7554/eLife.00659 Text en Copyright © 2013, Demarque and Schibler http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Genomics and Evolutionary Biology
Demarque, Maud
Schibler, Ueli
Shedding new light on circadian clocks
title Shedding new light on circadian clocks
title_full Shedding new light on circadian clocks
title_fullStr Shedding new light on circadian clocks
title_full_unstemmed Shedding new light on circadian clocks
title_short Shedding new light on circadian clocks
title_sort shedding new light on circadian clocks
topic Genomics and Evolutionary Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622228/
https://www.ncbi.nlm.nih.gov/pubmed/23580350
http://dx.doi.org/10.7554/eLife.00659
work_keys_str_mv AT demarquemaud sheddingnewlightoncircadianclocks
AT schiblerueli sheddingnewlightoncircadianclocks