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Genome-Level Analysis of Selective Constraint without Apparent Sequence Conservation

Conservation of function can be accompanied by obvious similarity of homologous sequences which may persist for billions of years (Iyer LM, Leipe DD, Koonin EV, Aravind L. 2004. Evolutionary history and higher order classification of AAA+ ATPases. J Struct Biol. 146:11–31.). However, presumably homo...

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Detalles Bibliográficos
Autores principales: Vakhrusheva, Olga A., Bazykin, Georgii A., Kondrashov, Alexey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622294/
https://www.ncbi.nlm.nih.gov/pubmed/23418180
http://dx.doi.org/10.1093/gbe/evt023