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Distinct Mutational Behaviors Differentiate Short Tandem Repeats from Microsatellites in the Human Genome

A tandem repeat’s (TR) propensity to mutate increases with repeat number, and can become very pronounced beyond a critical boundary, transforming it into a microsatellite (MS). However, a clear understanding of the mutational behavior of different TR classes and motifs and related mechanisms is lack...

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Detalles Bibliográficos
Autores principales: Ananda, Guruprasad, Walsh, Erin, Jacob, Kimberly D., Krasilnikova, Maria, Eckert, Kristin A., Chiaromonte, Francesca, Makova, Kateryna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622297/
https://www.ncbi.nlm.nih.gov/pubmed/23241442
http://dx.doi.org/10.1093/gbe/evs116