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The effect of weight in the outcomes of meningioma patients
BACKGROUND: Meningiomas are more prevalent in women and mostly benign in nature. Our aim was to evaluate the association of weight and outcomes of meningioma patients undergoing craniotomy. METHODS: A retrospective analysis of meningioma patients discharged postcraniotomy between 1998 and 2007 was c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622350/ https://www.ncbi.nlm.nih.gov/pubmed/23607067 http://dx.doi.org/10.4103/2152-7806.110023 |
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author | Dickinson, Holly Carico, Christine Nuño, Miriam Nosova, Kristin Elramsisy, Adam Patil, Chirag G. |
author_facet | Dickinson, Holly Carico, Christine Nuño, Miriam Nosova, Kristin Elramsisy, Adam Patil, Chirag G. |
author_sort | Dickinson, Holly |
collection | PubMed |
description | BACKGROUND: Meningiomas are more prevalent in women and mostly benign in nature. Our aim was to evaluate the association of weight and outcomes of meningioma patients undergoing craniotomy. METHODS: A retrospective analysis of meningioma patients discharged postcraniotomy between 1998 and 2007 was conducted. Univariate and multivariate analysis evaluated in-hospital mortality, complications, length of stay (LOS), and cost. RESULTS: According to the nationwide inpatient sample (NIS) database, an estimated 72,257 adult meningioma patients underwent a craniotomy in US hospitals during the study period. Female and male weight loss rates were 0.7% and 1.2%, respectively; obesity rates were 5.2% and 3.7%. Males had higher rates of malignant tumors than females (6.2% vs. 3.5%, P < 0.0001), and malignant tumors were more common in patients with weight loss (6.4% vs. 4.3%, P = 0.03). Weight loss was associated with higher mortality in men (OR 6.66, P < 0.0001) and women (OR 3.92, P = 0.04) as well as higher rates of postoperative complications in both men (OR 6.13, P < 0.0001) and women (OR 8.37, P < 0.0001). Furthermore, patients suffering weight loss had longer LOS and higher overall hospital cost when compared with all patients. In contrast, obesity seemed to reduce mortality (OR 0.47, P = 0.0006) and complications (OR 0.8, P = 0.0007) among women. CONCLUSIONS: In summary, weight loss seems to be the single most critical factor present in patients experiencing higher mortality, complications, hospital charges, and longer LOS. However, further studies aimed to assess the inter-relation of potential preexisting comorbidities and weight loss are needed to establish causation. |
format | Online Article Text |
id | pubmed-3622350 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36223502013-04-19 The effect of weight in the outcomes of meningioma patients Dickinson, Holly Carico, Christine Nuño, Miriam Nosova, Kristin Elramsisy, Adam Patil, Chirag G. Surg Neurol Int Original Article BACKGROUND: Meningiomas are more prevalent in women and mostly benign in nature. Our aim was to evaluate the association of weight and outcomes of meningioma patients undergoing craniotomy. METHODS: A retrospective analysis of meningioma patients discharged postcraniotomy between 1998 and 2007 was conducted. Univariate and multivariate analysis evaluated in-hospital mortality, complications, length of stay (LOS), and cost. RESULTS: According to the nationwide inpatient sample (NIS) database, an estimated 72,257 adult meningioma patients underwent a craniotomy in US hospitals during the study period. Female and male weight loss rates were 0.7% and 1.2%, respectively; obesity rates were 5.2% and 3.7%. Males had higher rates of malignant tumors than females (6.2% vs. 3.5%, P < 0.0001), and malignant tumors were more common in patients with weight loss (6.4% vs. 4.3%, P = 0.03). Weight loss was associated with higher mortality in men (OR 6.66, P < 0.0001) and women (OR 3.92, P = 0.04) as well as higher rates of postoperative complications in both men (OR 6.13, P < 0.0001) and women (OR 8.37, P < 0.0001). Furthermore, patients suffering weight loss had longer LOS and higher overall hospital cost when compared with all patients. In contrast, obesity seemed to reduce mortality (OR 0.47, P = 0.0006) and complications (OR 0.8, P = 0.0007) among women. CONCLUSIONS: In summary, weight loss seems to be the single most critical factor present in patients experiencing higher mortality, complications, hospital charges, and longer LOS. However, further studies aimed to assess the inter-relation of potential preexisting comorbidities and weight loss are needed to establish causation. Medknow Publications & Media Pvt Ltd 2013-04-03 /pmc/articles/PMC3622350/ /pubmed/23607067 http://dx.doi.org/10.4103/2152-7806.110023 Text en Copyright: © 2013 Dickinson H http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Original Article Dickinson, Holly Carico, Christine Nuño, Miriam Nosova, Kristin Elramsisy, Adam Patil, Chirag G. The effect of weight in the outcomes of meningioma patients |
title | The effect of weight in the outcomes of meningioma patients |
title_full | The effect of weight in the outcomes of meningioma patients |
title_fullStr | The effect of weight in the outcomes of meningioma patients |
title_full_unstemmed | The effect of weight in the outcomes of meningioma patients |
title_short | The effect of weight in the outcomes of meningioma patients |
title_sort | effect of weight in the outcomes of meningioma patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622350/ https://www.ncbi.nlm.nih.gov/pubmed/23607067 http://dx.doi.org/10.4103/2152-7806.110023 |
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