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AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging

Even in healthy individuals there is an inexorable agerelated decline in cognitive function. This is due, in large part, to reduced synaptic plasticity caused by changes in the molecular composition of the postsynaptic membrane. AMPA receptors (AMPARs) are glutamate-gated cation channels that mediat...

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Detalles Bibliográficos
Autores principales: Henley, Jeremy M., Wilkinson, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622464/
https://www.ncbi.nlm.nih.gov/pubmed/23576886