EGFP-EGF1-Conjugated PLGA Nanoparticles for Targeted Delivery of siRNA into Injured Brain Microvascular Endothelial Cells for Efficient RNA Interference

Injured endothelium is an important target for drug and/or gene therapy because brain microvascular endothelial cells (BMECs) play critical roles in various pathophysiological conditions. RNA-mediated gene silencing presents a new therapeutic approach for treating such diseases, but major challenge...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Mei, Heng, Shi, Wei, Deng, Jun, Zhang, Bo, Guo, Tao, Wang, Huafang, Hu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622655/
https://www.ncbi.nlm.nih.gov/pubmed/23593330
http://dx.doi.org/10.1371/journal.pone.0060860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622655/
https://www.ncbi.nlm.nih.gov/pubmed/23593330
http://dx.doi.org/10.1371/journal.pone.0060860

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