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EGFP-EGF1-Conjugated PLGA Nanoparticles for Targeted Delivery of siRNA into Injured Brain Microvascular Endothelial Cells for Efficient RNA Interference

Injured endothelium is an important target for drug and/or gene therapy because brain microvascular endothelial cells (BMECs) play critical roles in various pathophysiological conditions. RNA-mediated gene silencing presents a new therapeutic approach for treating such diseases, but major challenge...

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Detalles Bibliográficos
Autores principales:	Chen, Chen, Mei, Heng, Shi, Wei, Deng, Jun, Zhang, Bo, Guo, Tao, Wang, Huafang, Hu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622655/ https://www.ncbi.nlm.nih.gov/pubmed/23593330 http://dx.doi.org/10.1371/journal.pone.0060860

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