DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27(Kip1) activity in neuroblastoma

Neuroblastoma (NB) is the most common extracranial pediatric tumor. NB patients over 18 months of age at the time of diagnosis are often in the later stages of the disease, present with widespread dissemination, and often possess MYCN tumor gene amplification. MYCN is a transcription factor that reg...

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Detalles Bibliográficos
Autores principales: KOOMOA, DANA-LYNN T., GEERTS, DIRK, LANGE, INGO, KOSTER, JAN, PEGG, ANTHONY E., FEITH, DAVID J., BACHMANN, ANDRÉ S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622674/
https://www.ncbi.nlm.nih.gov/pubmed/23440295
http://dx.doi.org/10.3892/ijo.2013.1835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622674/
https://www.ncbi.nlm.nih.gov/pubmed/23440295
http://dx.doi.org/10.3892/ijo.2013.1835

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