Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B

Telbivudine is an L-nucleoside analogue with potent antiviral activity against hepatitis B virus (HBV). Clinical trials have shown that telbivudine has a more potent and sustained antiviral activity with a lower frequency of viral resistance than lamivudine. Although there are several reports concer...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun Hye, Park, Hana, Lee, Kun Ho, Ahn, Sang Hoon, Kim, Seung-Min, Han, Kwang-Hyub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622860/
https://www.ncbi.nlm.nih.gov/pubmed/23593614
http://dx.doi.org/10.3350/cmh.2013.19.1.82
_version_ 1782265878350397440
author Kim, Eun Hye
Park, Hana
Lee, Kun Ho
Ahn, Sang Hoon
Kim, Seung-Min
Han, Kwang-Hyub
author_facet Kim, Eun Hye
Park, Hana
Lee, Kun Ho
Ahn, Sang Hoon
Kim, Seung-Min
Han, Kwang-Hyub
author_sort Kim, Eun Hye
collection PubMed
description Telbivudine is an L-nucleoside analogue with potent antiviral activity against hepatitis B virus (HBV). Clinical trials have shown that telbivudine has a more potent and sustained antiviral activity with a lower frequency of viral resistance than lamivudine. Although there are several reports concerning the safety profile of telbivudine, most adverse events are described as mild and transient in nature. Here we report two cases of telbivudine-induced myopathy in patients with chronic hepatitis B who were siblings.
format Online
Article
Text
id pubmed-3622860
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher The Korean Association for the Study of the Liver
record_format MEDLINE/PubMed
spelling pubmed-36228602013-04-16 Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B Kim, Eun Hye Park, Hana Lee, Kun Ho Ahn, Sang Hoon Kim, Seung-Min Han, Kwang-Hyub Clin Mol Hepatol Case Report Telbivudine is an L-nucleoside analogue with potent antiviral activity against hepatitis B virus (HBV). Clinical trials have shown that telbivudine has a more potent and sustained antiviral activity with a lower frequency of viral resistance than lamivudine. Although there are several reports concerning the safety profile of telbivudine, most adverse events are described as mild and transient in nature. Here we report two cases of telbivudine-induced myopathy in patients with chronic hepatitis B who were siblings. The Korean Association for the Study of the Liver 2013-03 2013-03-25 /pmc/articles/PMC3622860/ /pubmed/23593614 http://dx.doi.org/10.3350/cmh.2013.19.1.82 Text en Copyright © 2013 by The Korean Association for the Study of the Liver http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Eun Hye
Park, Hana
Lee, Kun Ho
Ahn, Sang Hoon
Kim, Seung-Min
Han, Kwang-Hyub
Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
title Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
title_full Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
title_fullStr Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
title_full_unstemmed Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
title_short Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
title_sort two cases of telbivudine-induced myopathy in siblings with chronic hepatitis b
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622860/
https://www.ncbi.nlm.nih.gov/pubmed/23593614
http://dx.doi.org/10.3350/cmh.2013.19.1.82
work_keys_str_mv AT kimeunhye twocasesoftelbivudineinducedmyopathyinsiblingswithchronichepatitisb
AT parkhana twocasesoftelbivudineinducedmyopathyinsiblingswithchronichepatitisb
AT leekunho twocasesoftelbivudineinducedmyopathyinsiblingswithchronichepatitisb
AT ahnsanghoon twocasesoftelbivudineinducedmyopathyinsiblingswithchronichepatitisb
AT kimseungmin twocasesoftelbivudineinducedmyopathyinsiblingswithchronichepatitisb
AT hankwanghyub twocasesoftelbivudineinducedmyopathyinsiblingswithchronichepatitisb

Ejemplares similares