Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals

The sequence of guinea pig cytomegalovirus (GPCMV) was determined by direct sequencing of salivary gland homogenates obtained following sustained, serial in vivo passage of pathogenic virus in guinea pigs. The 233,501-nucleotide salivary gland (SG) genome was noted to have 11 differences compared to...

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Autores principales: Yang, Dongmei, Tamburro, Kristen, Dittmer, Dirk, Cui, Xiaohong, McVoy, Michael A., Hernandez-Alvarado, Nelmary, Schleiss, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622957/
https://www.ncbi.nlm.nih.gov/pubmed/23516193
http://dx.doi.org/10.1128/genomeA.00054-13
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author Yang, Dongmei
Tamburro, Kristen
Dittmer, Dirk
Cui, Xiaohong
McVoy, Michael A.
Hernandez-Alvarado, Nelmary
Schleiss, Mark R.
author_facet Yang, Dongmei
Tamburro, Kristen
Dittmer, Dirk
Cui, Xiaohong
McVoy, Michael A.
Hernandez-Alvarado, Nelmary
Schleiss, Mark R.
author_sort Yang, Dongmei
collection PubMed
description The sequence of guinea pig cytomegalovirus (GPCMV) was determined by direct sequencing of salivary gland homogenates obtained following sustained, serial in vivo passage of pathogenic virus in guinea pigs. The 233,501-nucleotide salivary gland (SG) genome was noted to have 11 differences compared to the tissue culture-passaged virus, although no variations were noted in putative protein coding sequences.
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spelling pubmed-36229572013-04-12 Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals Yang, Dongmei Tamburro, Kristen Dittmer, Dirk Cui, Xiaohong McVoy, Michael A. Hernandez-Alvarado, Nelmary Schleiss, Mark R. Genome Announc Viruses The sequence of guinea pig cytomegalovirus (GPCMV) was determined by direct sequencing of salivary gland homogenates obtained following sustained, serial in vivo passage of pathogenic virus in guinea pigs. The 233,501-nucleotide salivary gland (SG) genome was noted to have 11 differences compared to the tissue culture-passaged virus, although no variations were noted in putative protein coding sequences. American Society for Microbiology 2013-03-14 /pmc/articles/PMC3622957/ /pubmed/23516193 http://dx.doi.org/10.1128/genomeA.00054-13 Text en Copyright © 2013 Yang et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Yang, Dongmei
Tamburro, Kristen
Dittmer, Dirk
Cui, Xiaohong
McVoy, Michael A.
Hernandez-Alvarado, Nelmary
Schleiss, Mark R.
Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
title Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
title_full Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
title_fullStr Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
title_full_unstemmed Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
title_short Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
title_sort complete genome sequence of pathogenic guinea pig cytomegalovirus from salivary gland homogenates of infected animals
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622957/
https://www.ncbi.nlm.nih.gov/pubmed/23516193
http://dx.doi.org/10.1128/genomeA.00054-13
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