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Inactivated pep27 mutant as an effective mucosal vaccine against a secondary lethal pneumococcal challenge in mice
PURPOSE: A pep27 mutant may be able to elicit mucosal immunity against pneumococcal diseases, and could be employed as an inexpensive attenuated vaccine. However, this particular mutant contains an erythromycin-resistance marker. The purpose of the current study is to develop a markerless pep27 muta...
Autores principales: | Choi, Sang-Yoon, Tran, Thao Dang-Hien, Briles, David E., Rhee, Dong-Kwon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Vaccine Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623503/ https://www.ncbi.nlm.nih.gov/pubmed/23596592 http://dx.doi.org/10.7774/cevr.2013.2.1.58 |
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