The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes

The nexin–dynein regulatory complex (N-DRC) is proposed to coordinate dynein arm activity and interconnect doublet microtubules. Here we identify a conserved region in DRC4 critical for assembly of the N-DRC into the axoneme. At least 10 subunits associate with DRC4 to form a discrete complex distin...

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Detalles Bibliográficos
Autores principales: Bower, Raqual, Tritschler, Douglas, VanderWaal, Kristyn, Perrone, Catherine A., Mueller, Joshua, Fox, Laura, Sale, Winfield S., Porter, M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623635/
https://www.ncbi.nlm.nih.gov/pubmed/23427265
http://dx.doi.org/10.1091/mbc.E12-11-0801

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