Cargando…

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase

Glycoprotein 78 (Gp78) is a critical E3 ubiquitin ligase in endoplasmic reticulum–associated degradation. Overexpression of Flag-tagged Gp78 (Flag-gp78), but not Flag-gp78 mutated in its RING-finger domain (Flag-RINGmut) with deficient ubiquitin ligase activity, induces mitochondrial fragmentation a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Min, St-Pierre, Pascal, Shankar, Jay, Wang, Peter T. C., Joshi, Bharat, Nabi, Ivan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623636/ https://www.ncbi.nlm.nih.gov/pubmed/23427266 http://dx.doi.org/10.1091/mbc.E12-08-0607

Ejemplares similares

p38 MAP kinase–dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER–mitochondria association and mitochondria motility
por: Li, Lei, et al.
Publicado: (2015)

Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis
por: Joshi, Vibhuti, et al.
Publicado: (2017)

Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS
por: Alan, Parsa, et al.
Publicado: (2022)

Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases
por: Wang, Ying, et al.
Publicado: (2013)

The E3 Ubiquitin Ligases Hrd1 and gp78 Bind to and Promote Cholera Toxin Retro-Translocation
por: Bernardi, Kaleena M., et al.
Publicado: (2010)

SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78
por: Khodayari, Nazli, et al.
Publicado: (2017)

Ubiquitin Ligase gp78 Targets Unglycosylated Prion Protein PrP for Ubiquitylation and Degradation
por: Shao, Jia, et al.
Publicado: (2014)

Gp78, an E3 Ubiquitin Ligase Acts as a Gatekeeper Suppressing Nonalcoholic Steatohepatitis (NASH) and Liver Cancer
por: Zhang, Tianpeng, et al.
Publicado: (2015)

Huntingtin Interacts with the Cue Domain of gp78 and Inhibits gp78 Binding to Ubiquitin and p97/VCP
por: Yang, Hui, et al.
Publicado: (2010)

Ubiquitination of ERMES components by the E3 ligase Rsp5 is involved in mitophagy
por: Belgareh-Touzé, Naïma, et al.
Publicado: (2016)

Expression of Gp78/Autocrine Motility Factor Receptor and Endocytosis of Autocrine Motility Factor in Human Thyroid Cancer Cells
por: Wiseman, Sam M, et al.
Publicado: (2019)

The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy
por: Sun, Shan, et al.
Publicado: (2022)

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
por: Menzies, Sam A, et al.
Publicado: (2018)

Protein expression of the gp78 E3 ligase predicts poor breast cancer outcome based on race
por: Singhal, Sandeep K., et al.
Publicado: (2022)

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase
por: Jo, Youngah, et al.
Publicado: (2011)

FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels
por: Elcocks, Hannah, et al.
Publicado: (2023)

The Host E3-Ubiquitin Ligase TRIM28 Impedes Viral Protein GP4 Ubiquitination and Promotes PRRSV Replication
por: Cui, Zhiying, et al.
Publicado: (2023)

The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin
por: Hay-Koren, Avital, et al.
Publicado: (2011)

Ubiquitin ligases and beyond
por: Dikic, Ivan, et al.
Publicado: (2012)

Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination
por: Xu, Congfeng, et al.
Publicado: (2015)

New role of E3 ubiquitin ligase in the regulation of necroptosis
por: Seo, Jinho, et al.
Publicado: (2016)

Regulation of E3 ubiquitin ligases by homotypic and heterotypic assembly
por: Balaji, Vishnu, et al.
Publicado: (2020)

E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to Degeneration
por: Upadhyay, Arun, et al.
Publicado: (2017)

E3 Ubiquitin Ligase-Mediated Regulation of Osteoblast Differentiation and Bone Formation
por: Shen, Jianlin, et al.
Publicado: (2021)

Acacetin protects against depression-associated dry eye disease by regulating ubiquitination of NLRP3 through gp78 signal
por: Xie, Mingxia, et al.
Publicado: (2022)

Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase
por: Spratt, Donald E., et al.
Publicado: (2012)

AIRE Functions As an E3 Ubiquitin Ligase
por: Uchida, Daisuke, et al.
Publicado: (2004)

Structural Diversity of Ubiquitin E3 Ligase
por: Toma-Fukai, Sachiko, et al.
Publicado: (2021)

Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle
por: Perera, Sue, et al.
Publicado: (2012)

Regulation of LRRK2 Stability by the E3 Ubiquitin Ligase CHIP
por: Ding, Xiaodong, et al.
Publicado: (2009)

E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis
por: Sévère, N, et al.
Publicado: (2013)

Essential Roles of E3 Ubiquitin Ligases in p53 Regulation
por: Sane, Sanam, et al.
Publicado: (2017)

Regulation of Epithelial–Mesenchymal Plasticity by the E3 Ubiquitin-Ligases in Cancer
por: Rodríguez-Alonso, Andrea, et al.
Publicado: (2020)

Regulation of Metabolism by Mitochondrial MUL1 E3 Ubiquitin Ligase
por: Cilenti, Lucia, et al.
Publicado: (2022)

Regulation of ubiquitin ligase dynamics by the nucleolus
por: Mekhail, Karim, et al.
Publicado: (2005)

An ORFeome of rice E3 ubiquitin ligases for global analysis of the ubiquitination interactome
por: Wang, Ruyi, et al.
Publicado: (2022)

GpDSR7, a Novel E3 Ubiquitin Ligase Gene in Grimmia pilifera Is Involved in Tolerance to Drought Stress in Arabidopsis
por: Li, Mengmeng, et al.
Publicado: (2016)

ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20
por: Portney, Benjamin A., et al.
Publicado: (2018)

Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes
por: Liu, Shuxin, et al.
Publicado: (2020)

Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C
por: Paluda, Andrej, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7181gbiulsornfn0oqd9pekohr