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[(11)C]AF150(S), an agonist PET ligand for M1 muscarinic acetylcholine receptors

BACKGROUND: The M1 muscarinic acetylcholine receptor (M1ACh-R) is a G protein-coupled receptor that can occur in interconvertible coupled and uncoupled states. It is enriched in the basal ganglia, hippocampus, olfactory bulb, and cortical areas, and plays a role in motor and cognitive functions. Mus...

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Detalles Bibliográficos
Autores principales:	Buiter, Hans JC, Windhorst, Albert D, Huisman, Marc C, Yaqub, Maqsood, Knol, Dirk L, Fisher, Abraham, Lammertsma, Adriaan A, Leysen, Josée E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623648/ https://www.ncbi.nlm.nih.gov/pubmed/23514539 http://dx.doi.org/10.1186/2191-219X-3-19

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