Presence of alternative lengthening of telomeres associated circular extrachromosome telomere repeats in primary leukemia cells of chronic myeloid leukemia

BACKGROUND: The predominant mechanism by which human tumors maintain telomere length is via telomerase. In ~10% of tumor samples, however, telomere length is conserved, despite no detectable telomerase activity, in part through activation of the alternative lengthening of telomeres (ALT) pathway. ME...

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Detalles Bibliográficos
Autores principales: Samassekou, Oumar, Malina, Abba, Hébert, Josée, Yan, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623713/
https://www.ncbi.nlm.nih.gov/pubmed/23547895
http://dx.doi.org/10.1186/1756-8722-6-26

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