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Interferon-Inducible Mechanism of Dendritic Cell-Mediated HIV-1 Dissemination Is Dependent on Siglec-1/CD169

Human immunodeficiency virus type 1 (HIV-1) interactions with myeloid dendritic cells (DCs) can result in virus dissemination to CD4(+) T cells via a trans infection pathway dependent on virion incorporation of the host cell derived glycosphingolipid (GSL), GM3. The mechanism of DC-mediated trans in...

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Detalles Bibliográficos
Autores principales:	Puryear, Wendy Blay, Akiyama, Hisashi, Geer, Suzanne D., Ramirez, Nora P., Yu, Xinwei, Reinhard, Björn M., Gummuluru, Suryaram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623718/ https://www.ncbi.nlm.nih.gov/pubmed/23593001 http://dx.doi.org/10.1371/journal.ppat.1003291

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