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A CD19/Fc fusion protein for detection of anti-CD19 chimeric antigen receptors

BACKGROUND: Chimeric Antigen Receptors (CARs) consist of the antigen-recognition portion of a monoclonal antibody fused to an intracellular signaling domain capable of activating T-cells. CARs displayed on the surface of transduced cells perform non-MHC-restricted antigen recognition and activating...

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Detalles Bibliográficos
Autores principales: De Oliveira, Satiro N, Wang, Jiexin, Ryan, Christine, Morrison, Sherie L, Kohn, Donald B, Hollis, Roger P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623748/
https://www.ncbi.nlm.nih.gov/pubmed/23360526
http://dx.doi.org/10.1186/1479-5876-11-23

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