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Host Cell Entry of Respiratory Syncytial Virus Involves Macropinocytosis Followed by Proteolytic Activation of the F Protein

Respiratory Syncytial Virus (RSV) is a highly pathogenic member of the Paramyxoviridae that causes severe respiratory tract infections. Reports in the literature have indicated that to infect cells the incoming viruses either fuse their envelope directly with the plasma membrane or exploit clathrin-...

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Detalles Bibliográficos
Autores principales: Krzyzaniak, Magdalena Anna, Zumstein, Michael Thomas, Gerez, Juan Atilio, Picotti, Paola, Helenius, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623752/
https://www.ncbi.nlm.nih.gov/pubmed/23593008
http://dx.doi.org/10.1371/journal.ppat.1003309